Photo by Kevin Jung-Hoo Park
B.Sc. Psychology & Neuroscience. Ph.D. Neuroscience, University of Manchester. Post Doctoral Fellow, McGill University.
Andy Greenhalgh, born in Yorkshire, United Kingdom, grew up in the post-industrial city of Bradford before studying Neuroscience at the University of Manchester. After completing his PhD, Greenhalgh moved to Montreal for his postdoctoral training and will start an independent research career in Bordeaux, France later this year.
Andy Greenhalgh’s fundamental research interest is the immune system’s role in central nervous system (CNS) injury and disease. More specifically his focus is on the role of inflammation after a physically traumatic event, such as a spinal cord injury. During his postdoctoral training at McGill University, he began to investigate important cells involved in the immune response following a spinal cord injury; namely microglia and macrophages. These are key cells involved in the recovery of spinal cord tissue. Microglia are the brain and spinal cord’s resident immune cell, whereas macrophages infiltrate the CNS from the blood after injury. Using multiple techniques, Greenhalgh has collected novel data which shows infiltrating macrophages signaling to resident microglia within the CNS, altering their function during injury. Greenhalgh and his colleagues have identified the signaling mechanism by which they interact and believe targeting this pathway could have great implications on long-term recovery after CNS injury.
Design, Concordia University.
Cellular Kinesics is an exploration of the communication methods of cells during a spinal cord injury. Heavily influenced by the research data, videos, and imaging of Andrew Greenhalgh, this work is a collaborative effort of science and art. In this project, we blend the art of hand-lettering with the actions of two phagocytic cells. The goal of illustrative hand-lettering is to have the letter forms express its meaning through clear visual representation. This goal is translated with Cellular Kinesics by highlighting the key moments of communication between the microglia and macrophages after an injury occurs in the spinal cord. The letters evolve, in this case, through four major actions: pre-injury; first responders (microglia); relieve, second responders (macrophages); necrosis or cellular death (macrophages). Illustrative hand-lettering is able to take the dense realities of scientific language and make them accessible for those unfamiliar with the language of cells.
Photo by Tia Besser-Paul
Cellular Kinesics, 2017.
Tia Besser-Paul and Andrew Greenhalgh, Booklet: silk paper black and white print, Poster: poster paper black and white print.
Photo by Tia Besser-Paul
Photo by C. Zaelzer